Fluorinated Opioid relieves pain without side effects

Volume 95 Issue 10 | p. 8 | News of The Week
Issue Date: March 6, 2017 | Web Date: March 3, 2017

An opioid minus major side effects

Fluorinated version of fentanyl is active only in areas of inflammation, eliminating troublesome effects in rats

By Bethany Halford

When given to rats, a new opioid relieves their pain but doesn’t cause the negative side effects typically associated with this class of analgesic, such as addiction, respiratory depression, and constipation (Science 2017, DOI: 10.1126/science.aai8636). “These things are big problems when we treat patients for long periods of time with opioids,” says Christoph Stein, a professor of anesthesiology and critical care medicine at . . .


I will post the remained of this soon